Oncology - Serbian Journal of the Medical Chamber
INTRODUCTION
Breast tumors that belong to the category of phyllodes tumors (PT), and are also referred to as cystosarcoma phyllodes, account for less than 1% of all breast tumors. Their incidence is about 2.1 per one million [1,2,3].
Traditionally, phyllodes tumors containing both stromal and...
INTRODUCTION
Herbal medicine (phytotherapy) is the oldest form of treatment that uses plants and plant derivatives due to their medicinal properties [1].
The use of plants was the basis for the development of modern medicine, and in some rural and indigenous areas, they represent the only...
INTRODUCTION
Modern treatment of malignant diseases has significantly improved the prognosis and survival of hemato-oncology patients [1]. In the past forty years, the ten-year survival of patients with non-Hodgkin lymphomas has increased from 20% to over 65% [2]. In addition, malignant diseases...
INTRODUCTION
Acute lymphoblastic leukemia (ALL) is a heterogeneous disease characterized by the malignant transformation and proliferation of lymphoid progenitor cells in the bone marrow, peripheral blood, and other tissues [1].
The incidence of ALL in Europe is 1.28 per 100.000 individuals...
INTRODUCTION
Coronavirus disease (COVID-19), caused by the SARSCoV-2 virus, is primarily a respiratory disease, with possible systemic effects. First identified in Wuhan City, in December 2019, in the ensuing months the disease spread worldwide and was declared a pandemic by the World Health...
INTRODUCTION
The cytomegalovirus (CMV) is a ubiquitous herpes virus, whose name stems from the enlargement of the infected cells, i.e., they are cytomegalic.
The prevalence of CMV seropositivity varies in the world from 60% do 100%. Primary infection usually occurs in early childhood, and in...
INTRODUCTION
Acute myeloid leukemias (AML) are a heterogenous group of malignant diseases of the blood characterized by clonal expansion of myeloblasts in the bone marrow (≥20%), in peripheral blood, and/or in other tissues [1]. AML is a rare disease and accounts for 1.1% of all malignant...
INTRODUCTION
Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer characterized by the proliferation of malignant epithelial cells within the ductal system, without breaching the basement membrane or infiltrating the surrounding tissue [1]. Although it does not have metastatic...
INTRODUCTION
Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors represent an optimal therapeutic option in the first or second line of treatment for metastatic hormone receptor-positive (HR+), human epidermal growth factor receptor 2 (HER2)-negative breast cancer. These drugs are administered...
INTRODUCTION
Autologous hematopoietic stem cell transplantation (AHSCT) represents the standard approach to the treatment of hematological malignancies. The main indications for AHSCT are multiple myeloma and lymphoma. As of late, this approach has shown a growing potential in the treatment of...
INTRODUCTION
Central nervous system involvement in multiple myeloma (CNS-MM) is a very rare entity with an incidence lower than 1% of all extramedullary multiple myeloma [1]. Over the past decade, an increase in the incidence of this entity was observed, primarily due to the improvement of...
INTRODUCTION
The concept of cardiotoxicity in the context of cancer treatment was first mentioned in the early 1970s [1]. In 2020, nearly 20 million new cancer cases were diagnosed worldwide, while approximately 10 million oncology patients died during the same year [2]. Over the past 30...
INTRODUCTION
Extramammary Paget’s disease (EMPD) is a rare intraepithelial malignancy that typically occurs in areas rich in apocrine glands, such as the perineum, vulva, axilla, scrotum, and penis [1]. The exact pathogenesis of EMPD is still not completely understood. Current data indicate that...
INTRODUCTION
Acute leukemias (AL) are malignant clonal diseases of the hematopoietic stem cell, occurring due to anomaly in the stem cell genome, and resulting in uncontrolled proliferation and infiltration of different tissues [1].
Acute myeloid leukemia (AML) is characterized by pathological...
INTRODUCTION
Acute myeloid leukemia (AML) is a heterogenous clonal malignant disease of the hematopoietic tissue wherein immature hematopoietic cells proliferate and accumulate in the bone marrow, peripheral blood, and other tissues [1].
AML is a rare malignant disease of hematopoietic...
INTRODUCTION
Acute myeloid leukemia (AML) is a heterogenous malignant disease which is characterized by clonal proliferation of a precursor cell of the myeloid lineage. The accumulation of immature cells – blasts, leads to progressive insufficiency of bone marrow and the infiltration of the...
INTRODUCTION
Melanoma, a malignant tumor of melanocytes, presents significant treatment challenges due to its aggressive nature and tendency to metastasize. The advent of targeted therapies, particularly BRAF and MEK inhibitors, has revolutionized the management of BRAF-mutant melanoma, leading...
INTRODUCTION
Medullary thyroid carcinoma (MTC) is a rare tumor, accounting for 5% of thyroid malignancies. MTC is an aggressive tumor, associated with a significantly poorer prognosis compared to other types of thyroid cancer [1]. MTC is responsible for approximately 13% of deaths related to...
INTRODUCTION
Osteosarcomas account for 10%–15% of all primary malignant tumors of the chest wall, which, in turn, account for only 1%–2% of all primary tumors [1]. The association between radiotherapy (RT) applied as a part of breast cancer oncological treatment and the occurrence of...
INTRODUCTION
Thrombotic microangiopathies (TMA) are a group of diseases characterized by disseminated intravascular thrombosis, thrombocytopenia and ischemic organ damage. This group includes thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS) [1].
Thrombotic...
